Patient recruitment is extensively accepted as a vital factor of success for paid medical trials. Although, a considerable amount of trials for companies (like HMR Bridging Studies) aren’t able to reach their recruitment objectives—a situation that has important scientific, financial, ethical, and policy implications.
Additionally, there are significant effects on stakeholders who directly contribute to the trial including investigators, sponsors, and study participants. Despite efforts over multiple decades to identify and address barriers, recruitment challenges persist.
Here are some tips on how to facilitate clinical trial recruitment:
Develop A Patient-Centric Enrollment Process
The MRC UK proposes that before a trial begins, organizations should talk to representatives from local stakeholder groups to track their influence on the design and to foster their sense of possession of the trial. Also, the Council recommends, a feasibility study should be undertaken to determine possible figures for suitable applicants from each potential site.
A patient interested in participating in a trial should be identified before a site is established. Individual, personalized and patient-centric medicine represents the future of clinical research, notably in oncology.
We need to write protocols and plan recruitment strategies based on individual patient needs and not on a disease class. By putting the availability of patients at the center of trial site introduction, expenditure can be saved and a wider spread of suitable patients can be tapped across multiple sites.
Outline The Benefits Of Participating In The Study
It’s vital to take a good amount of time researching your possible participants whilst you can. Understanding the people participating in the study can give you a nice amount of insight into how successfully you can reach out to your possible patients. Discover what is motivating people to join the study. Are they searching for a new treatment? Do they have a lack of health insurance and are hoping for medical care at no cost?
Now it is time to choose how you’re going to pay participant. Develop a budget to stimulate the study, as well as to compensate the patients for travel and inconvenience.
What are the potential fees for spending on advertising? Will you reimburse your patients with travel allowances, gift cards, or salaries for their absence at work? Be transparent and have a well-thought-out plan. This can present your study in a legitimate way and avoid any severe misunderstandings. It’s imperative that everything is clear and concise.
Offer Financial Incentives For Patients
Although monetary motivations in healthcare are debatable, the MRC proposes that giving modest payments for the patients’ trouble, a practice with a long tradition, can be extremely effective. The first to offer financial compensation for research participation was Walter Reed, who in 1901 run the team that hypothesized and confirmed the theory that yellow fever is spread by a particular mosquito species, rather than by direct contact. He paid volunteers $100 in gold for participation and offered a bonus of $100 for successful infection with yellow fever, payable to family in the event of death. Nowadays, 24-80% of research organizations and academic medical centers pay at least some participants.
There are, of course, hundreds of different types of trials, ranging from CRO laboratory services trials, screening trials, CRO pharmacy trials and many more. All different trials will need different approaches. Make sure you understand what is needed before embarking on recruiting patients for your trial.